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Kikuno Ran Swallowing Continuously Fpre084 Link _hot_

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| Finding | What it means | Numbers (healthy adults) | |---------|----------------|--------------------------| | | The first 6–8 swallows are a ramp‑up; thereafter, frequency stabilises at ~1.5 Hz. | Mean interval = 0.68 ± 0.04 s | | Mild muscular fatigue | Cervical force drops ~12 % over 10 min, but pressure generation stays within 5 % of baseline—suggesting neuromuscular compensation . | Peak force: 4.2 N → 3.7 N | | Respiratory coupling | Each swallow aligns with the post‑inspiratory phase of breathing, preserving airway safety. | 92 % of swallows occur <150 ms after inspiratory offset | | Metabolic cost | Continuous swallowing consumes ~0.04 kcal/min—negligible in the context of endurance sport but measurable in tight energy budgets (e.g., space missions). | ΔVO₂ = +0.2 mL·kg⁻¹·min⁻¹ | | EEG “burst‑suppression” pattern | Brainstem nuclei show a transient high‑frequency burst preceding each swallow, followed by a brief suppression —a potential biomarker for swallow readiness. | 8–12 Hz bursts, 50‑70 ms duration | | Age‑related slowdown | Elderly participants show a 15 % slower steady‑state frequency and a 25 % greater force decay, confirming age‑related endurance loss . | 1.3 Hz vs. 1.5 Hz, force drop 16 % vs. 12 % |

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